In this Omics Logic Metagenomics Specialization, we will explore how different types of analysis can be used to understand the microbial world. We will cover several bioinformatics approaches to the analysis of the microbiome. We will learn to compare microbial composition in different conditions, learn about the sequencing of viral samples and discuss how microbes evade the immune response of the host as well as evade treatment. We will do so in the context of several projects taken from high-impact publications. Program Topics - NGS: 16s metagenomics sequencing - Microbiome - functional bacterial community - Ribosomal RNA, Hypervariable regions (HVRs) - Operational Taxonomic Units (OTUs) - Mapping short reads on reference databases - DADA2 pipeline for amplicon sequencing - Viral genome detection in metagenomic data - Evolution, fitness, and quasi-species.
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