It's updated guide to flasks sustain on bosses for Chains of Command build I've made in 3.16 ([ Ссылка ])
The most important nerf that hits build near fatally was removing Survival Secrets jewel from the game. But there are still options to sustain flasks on bosses.
My setup allows to sustain flasks on bosses. Also it allows me to have permanent uptime of Replica Sorrow of the Divine for permanent Eldritch Battery. In combination with MoM and another useful passive from the bottle (Life Recovery from Flasks also applies to Energy Shield during Effect) provides incredible extra defense layer. It's nearly impossible for me to get killed by many small hits, because my insta heal flasks effect is literally doubled and they refill really fast.
Important gear and skills/masteries:
1. Brutal Restraint jewel of Balbala that gives 10% Flask charges gained (1 node is required, the more the merrier)
2. Two Fasting from medium jewels (with 6% flask duration )
3. Essence Extraction skills circle with mastery +1 mana/+1 hp flask charge every 3 seconds.
Notable mentions:
1. Spiked Concoction (for Alchemist's Genius) from medium jewel
2. Replenishing Remedies skill taken as annoint.
