Dr. Aubrey de Grey discusses the changing priorities at the forefront of the field of longevity rejuvenation research at Lifespan.io's 2021 EARD conference. “The crusade is accelerating”, says Dr. De Grey, “but there’s so much still to do.”
De Grey is the author of The Mitochondrial Free Radical Theory of Aging (1999) and co-author of Ending Aging (2007). He is an international adjunct professor of the Moscow Institute of Physics and Technology, a fellow of the Gerontological Society of America, the American Aging Association, and the Institute for Ethics and Emerging Technologies.

SENS Research Foundation works to develop, promote, and ensure widespread access to therapies that cure and prevent the diseases and disabilities of aging by comprehensively repairing the damage that builds up in our bodies over time.

The annual Ending Age-Related Diseases (EARD) conference by Lifespan.io brings together longevity thought leaders together to exchange research reports, inspire and get inspired with new ideas, find collaborators, supporters, and mentors.

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It's great to be here, of course. I just thought I'd start by saying that some of you may have heard perhaps of a complication that's going on in my life right now. I just wanted to say that there is an independent investigation, which was started at the beginning of July and is still ongoing. That, of course, means a couple of things.

First of all, it means that I am on administrative leave, which means that I am not representing SENS Research Foundation here today; officially, I am here in a personal capacity. I should mention that I just noticed I have the SENS Research Foundation logo at the bottom of all my slides, so please pretend that that isn't there.

Apart from that, I can't say anything more at all about what's going on; of course, this would be the wrong place anyway. I just want to say how overwhelmed I am for all the love and support that I've received from hundreds and hundreds of people, and it shouldn't be long now. So you know, watch this space. So, having said all that, let me share my screen.

I thought I would talk today about the changing priorities that I see that we have in this field at the moment, because it's very easy to get very optimistic and excited about how things are going. No question, things are moving much faster than they were even a few years ago, but I believe that those of us here who are really at the forefront of this crusade need to be absolutely clear that there is an awful lot still to do.

I thought I would start in illustrating that by using some of the slides that you're very familiar with but with different titles than you may have seen. Of course, you know about this, it's the increase in life expectancy that has happened over the past couple of centuries, and, of course, that's a wonderful thing.

It is the result of progress that we have made initially in the elimination or virtual elimination of infant mortality from things like tuberculosis. And subsequently, as we've gone on, the reduction in mortality rates at older ages, which has been absolutely wonderful. And it has certainly resulted in greater quantity of life and quality of life.

But as we all know, the result is that more and more people are reaching ages at which they suffer from the chronic progressive health problems of late life. As usual, I'm just putting up this slide showing the economic outcome of that, which is completely catastrophic, in terms of the rate at which we are having to increase the proportion of the economy that is allocated to medical care. It's completely terrifying, and something better be done about it.

Of course, that is very much in the minds of people across the board, policymakers, the private sector and so on. But, what to do about it is something that, of course, we have rather less consensus on as things stand. I mentioned all that because it kind of illustrates how priorities change, that when you identify a particular problem or a particular bottleneck, and you make progress on it, other ones pop up in their place.

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