No, for a small studio, other than the cost difference, you can use TRS in the place of TS cables. ... EDIT: thinking about it, there may be some slight durability difference in the two types of cables as well, if you are using the TRS cables in applications where they get flexed often, such as for a guitar cable.Typically, a TRS connection is used for mono unbalanced audio plus video, and a TRRS connection for stereo unbalanced audio plus video. Cables designed for this use are often terminated with RCA connectors on the other end. ... Hands-free sets and headsets often use 3.5 mm or 2.5 mm connectors.A TRS Cable is unique in that it can carry either a balanced audio signal or an unbalanced stereo signal. So when the common question, “Are TRS cables balanced?” arises, the answer seems somewhat vague: “They can be.” Whether a TRS cable is balanced or not depends on what it is connecting.TRS is the abbreviation for “Tip, Ring, Sleeve.” It looks like a standard 1/4″ or 1/8″ plug but with an extra “ring” on its shaft. TRS cables have two conductors plus a ground (shield). They are commonly used to connect balanced equipment or for running both left and right mono signals to stereo headphones.

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