Lesson on the Carnitine Shuttle. Carnitine is an important metabolite derived from our diet or biosynthesized from lysine and methionine. Since the mitochondrial inner membrane is impermeable to long chain fatty acids, carnitine is used as a shuttle molecule (a carrier system) to transport long chain fatty acids into the mitochondrial matrix for beta oxidation. Once carnitine has shuttled the fatty acyl chain into the mitochondrial matrix, carnitine can be regenerated and transported back out into the cytosol to be used again for fatty acid transport.

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**MEDICAL DISCLAIMER**: JJ Medicine does not provide medical advice, and the information available on this channel does not offer a diagnosis or advice regarding treatment. Information presented in these lessons is for educational purposes ONLY, and information presented here is not to be used as an alternative to a healthcare professional’s diagnosis and treatment of any person/animal.

Only a physician or other licensed healthcare professional are able to determine the requirement for medical assistance to be given to a patient. Please seek the advice of your physician or other licensed healthcare provider if you have any questions regarding a medical condition.

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