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Special Thanks to my team and Nicholas Norwitz - Oxford Ketone PhD Researcher and Harvard Med Student - for working diligently on this research!


10 Thyroid Facts in 5 Minutes that YOU NEED to KNOW!- Thomas DeLauer


1.) T3 is active thyroid hormone. You may have heard about TSH, T4, and T3. TSH is released by the brain to cause the production of inactive T4 thyroid hormone in the thyroid gland. T4 then travels to the liver, where it’s converted into active T3 thyroid hormone.

2.) The Thyroid Operates by “negative feedback.” As with many hormonal axes, thyroid hormone inhibits its own production. Specifically, T3 inhibits the release of TSH. This system is designed to keep active T3 within a narrow range that the body likes.

3.) Low T3 and/or high TSH is a sign of an underactive thyroid. Since T3 is active thyroid hormone, low T3 suggests a person is hypothyroid, right? Not necessarily. You see, your body can adjust its sensitivity to T3 so that you get more bang for your hormonal buck. If your T3 is low and your TSH is high, this clearly indicates you are hypothyroid because the negative feedback system is trying to produce more thyroid hormone. However, to complicate matters further, your body can adjust the T4 to T3 conversion rate along with its sensitivity to T3 negative feedback. This means that some people can, in fact, be hypothyroid with low T3 and a normal T4 and TSH. In summary, if you have a low T3 and high TSH, you are hypothyroid. If you have a low T3 and normal TSH, you may or may not be hypothyroid.

4.) Hypothyroidism is more common in the elderly. Things slow down as you get on. Apologies.

5.) Hypothyroidism is more common in women. This is, in part, because estrogen increases thyroid hormone binding globulin and can, therefore, decrease free thyroid hormone in the blood.

6.) Birth control can cause hypothyroidism. Unfortunately, the pill, and other forms of hormonal contraception, can cause certain vitamin and mineral deficiencies – folic acid, vitamins B2, B6, B12, vitamins C and E, magnesium selenium, and zinc – that can affect the thyroid.

7.) Your thyroid needs iodine. Thyroid hormone is made from the amino acid tyrosine and the mineral iodine. Rich sources of iodine are cod, tuna, shrimp, seaweed, and iodized table salt.

8.) You need selenium for make T3. The enzymes in your liver depend on the mineral selenium to convert T4 into active T3. Brazil nuts are an amazing source of selenium. Just one brazil nut per day will get you your daily dose. Tuna is another good source of selenium.

9.) Low T3 may be good for longevity. Studies show that lower T3 levels are correlated with longer lifespans. It’s like the opposite of “burn hot die young.”

10.) Ketogenic diets may uniquely affect your thyroid. As with all diets, a ketogenic diet that is effectively implemented for weight loss will decrease your T3 simply because you lose weight. However, unlike other diets, this decrease in T3 observed in people on a ketogenic diet doesn’t appear to translate into a decrease in metabolic rate! This is taken to mean that a ketogenic diet may increase your sensitivity to T3 and, therefore, can help dieters escape the thyroid gland’s effort to sabotage your weight loss.

Nicholas Norwitz - Oxford Ketone PhD Researcher and Harvard Med Student: [ Ссылка ]

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