In 1997 there were 432 new patents for herbicides, by 2009 there were only 65. The development of broad spectrum glyphosate and “Roundup Ready crops” was a game changer that worked so well people basically stopped looking for new herbicides. That is until the weeds started fighting back.

Chemical & Engineering News article on the search for new modes of action
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Introduction to the Shikimate Pathway
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Credits:
Executive Producer:
Matthew Radcliff

Producers:
Elaine Seward
Andrew Sobey
Darren Weaver

Host:
Alex Dainis

Scientific Consultants:
Mark Loux, PhD
Patrick J. Tranel, PhD
Todd Gaines, PhD
Mithila Jugulam, Ph.D.
Leila Duman, PhD
Brianne Raccor, PhD

Executive in Charge for PBS: Maribel Lopez
Director of Programming for PBS: Gabrielle Ewing
Assistant Director of Programming for PBS: John Campbell


Reactions is a production of the American Chemical Society.
© 2022 American Chemical Society. All rights reserved.


Additional Sources:
Molecular basis for the herbicide resistance of Roundup Ready crops
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THE SHIKIMATE PATHWAY
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Why have no new herbicide modes of action appeared in recent years?
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The Pitfalls of Relating Weeds, Herbicide Use, and Crop Yield: Don't Fall Into the Trap! A Critical Review
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The cost of herbicide resistance
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Development and Characterization of a CP4 EPSPS-Based, Glyphosate-Tolerant Corn Event
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Tyrosine Biosynthesis, Metabolism, and Catabolism in Plants
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Biosynthesis and Metabolic Fate of Phenylalanine in Conifers
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Auxin driven indoleamine biosynthesis and the role of tryptophan as an inductive signal in Hypericum perforatum (L.)
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Finding of No Significant Impact
Animal and Plant Health Inspection Service
Petition for Non-regulated Status for Soybean Line MON 89788 (APHIS 06-178-01p)
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Glyphosate resistance: state of knowledge
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