Bupropion, sold under brand name Wellbutrin, is indicated for major depressive disorder. This drug also produces weight loss and among the bupropion side effects sedation is one of the important adverse effect to be considered. This medication is also indicated for cessation of smoking.
Major depressive disorder is associated with a few of the depressive symptoms like insomnia, lack of sleep, and either increase or decrease in the appetite. Depression may and few of the other symptoms like agitation, mental retardation, another important symptom is the pessimism, the negative thoughts on the patients and loss of libido, fatigue, feeling of guilt, which is one of the important indicator of the depression, and apathy, lack of initiation, suicidal initiation, all these are the symptoms of depression and when these symptoms are persisting in the patients drugs like antidepressants are given but among these antidepressants
Bupropion is one of the atypical antidepressant with somewhat better profile compared with the typical antipsychotics. For cessation of smoking also, bupropion can be used.
One of the important precautions of the bupropion is the psychotic symptoms. It can develop few of the psychotic symptoms like hallucinations, delusions, and even mental confusion, impaired concentration. This is particularly observed when it is used for the bipolar depression. It can also increase the manic phase in the patients.
Another important precaution, bupropion can increase the suicidal risk. That's why the treatment should be carefully monitored.
It can also produce few of the allergic reactions which may bring fever, rashes and few of the painful conditions like the arthralgia, and myalgia, joint and muscle pain.
Bupropion can cause weight loss by activation of the POMC neurons, pre-opiomelanocortin neurons which are going to control the appetite.
Important side effects of bupropion include dry mouth, constipation, nausea and vomiting headache. It can also increase the agitation and tremors. This drug can also produce a disturbance in the sleep resulting in the insomnia and dizziness. Elevation in blood pressure is also observed in few of the patients.
This drug is available as a tablet at different strengths, like 100 mg and 200 mg. It is also available as a SR tablet, at a dose of 150 mg.
To know when to avoid use of Wellbutrin, watch the following video.
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To learn about combination of bupropion and naltrexone for treatment of obesity, watch this video here. [ Ссылка ]
