Presented By: Anindita Basu, PhD

Speaker Biography: The basic units of biological structure and function are cells, which exhibit wide variation in regard to both type and state. We assess such variation by simultaneously profiling the transcriptomes of thousands of single mammalian cells or nuclei, using high-throughput emulsion microfluidics and DNA barcodes. When extracting intact cells from tissues and organs is technically challenging or impossible, single-nucleus RNA sequencing can provide an alternative way to obtain transcriptome profiles of such tissues.

Webinar: Single-cell Genomics Tools for Better Understanding and Treatment of Human Disease

Webinar Abstract: Basu leads a multi-disciplinary research group located at University of Chicago and Argonne National Laboratory and uses genomics, microfluidics, imaging and nano/bio-materials to develop new tools to aid in diagnosis and treatment of disease. She trained in Soft Matter Physics during Ph.D., followed by post-doctoral studies in Applied Physics, Molecular Biology and Bioinformatics. Her group combines materials, micro-fabrication, device capabilities and nano-scale imaging at Argonne with genomics, medicine, microbiology, and immunology at UChicago to build cross-disciplinary techniques to address pressing questions in biology and medicine.

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