History of DNA, Photo51, and overview of DNA Sequencing techniques. This is a live-stream recording of the MSc and PhD lecture series: #Bioinformatics for plant and animal sciences, given digitally during the Covid19 pandemic at the Humboldt University in Berlin organized and lectured by Dr Danny Arends.
#Lectures @ [ Ссылка ]
#Programming #Assignments and #Answers @ [ Ссылка ]
#Playlist: [ Ссылка ]
Chapters:
0:00 Welcome and some more terminology
0:16 History of #DNA
5:00 #Photo51 and the discovery of the double helix
6:07 Three types of DNA (A, B, and Z)
9:16 History of DNA Sequencing techniques
12:15 How Maxam-Gilbert sequencing works
18:06 How #pyrosequencing works
21:08 How Sanger sequencing works
26:23 Next generation sequencing
30:20 Single cell sequencing using #PacBio and Oxford Nanopore
35:45 Ion Torrent sequencing and homopolymer errors
40:22 Next generation sequencing by pyrosequencing
43:23 Sequencing by synthesis (#Illumina)
47:28 Sequencing by ligation (#SOLID sequencing)
51:46 Overview of Next Gen sequencing techniques and further reading
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