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Video description :-

What are lymphoblast cells ?

Hello every one , welcome to Aladdin creations …
In this short video I am going to discuss about

• What are the lymphoblasts
• Morphology of lymphoblast
• Why & when increase these cells


So let’s begin this …

Acute lymphoblastic leukemia is a type of cancer of the blood and bone marrow .
The National Cancer Institute estimates 5,960 people will receive a diagnosis of ALL in the United States in 2018.
Acute lymphocytic leukemia is the most common type of cancer in children, and we can see increase number of special type of cells , LYMPHOBLAST



Normally lymphoblasts are found in the bone marrow, but in acute lymphoblastic leukemia , lymphoblasts proliferate uncontrollably and are found in more than 20% in born marrow and large numbers in the peripheral blood as well.
So lymphoblast cells are , really good clue to identify & differentiate ALL

Lymphoblast is the progenitor cell of type of WBC call , T and B lymphocytes.
They either remain in the bone marrow or migrate to the thymus gland in the chest.
And this differentiation process of lymphoblast into lymphocytes , call as Lymphopoiesis.

When we consider cell Morphology
lymphoblasts are round in shape , The size is between 10 and 20 μm.
The nucleus of the lymphoblast , is round and contains compacted chromatin.
Also nuclear to cytoplasm ratio is very high there , we can see very scanty cytoplasm.
And it does not contain prominent nucleoli and cytoplasmic granules.

As I previously explain ,
When there is overproduction of lymphoblasts in the bone marrow, it gives rise to acute lymphocytic leukemia (ALL). this condition, we can usually see with , recurrent infections such as pneumonia .








Lymphoblast cells also use for cell culture purpose …







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