In this video, we have explained the neurobiology of seizures or convulsion and development of epilepsy or epileptogenesis.
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Our brain is a complex organ, it produces electrical impulses which control our movement, thoughts, and even memories.
These electrical impulses are transmitted by neurons, a network of cells that are found in the brain and throughout the body. Neurons transmit an electrical impulse and send ‘messages’ to nearby neurons and the rest of the body using neurotransmitters, a kind of chemical messenger. Now, what happens when this rhythmic impulse does not follow its rhythmic pattern?
There will be a series of electrical impulses, generated in the brain without any coordination with one another, inducing a seizure.
Multiple mechanisms can produce seizures, and they often appear to have no common thread. Seizures, on the other hand, occur when mechanisms that typically maintain a balance of excitation and inhibition fail.
As a result, there are typically safeguards in place to prevent neurons from generating too many action potentials, but there are also mechanisms in place to stimulate neuronal firing so that the nervous system can work properly. Seizures can be caused by disrupting or encouraging systems that limit firing or facilitate excitement.

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