In the June edition of our Research Seminar Series, Dr. Benedict C. Albensi presents groundbreaking research on mitochondrial function and its pivotal role in Alzheimer's disease.
Dr. Albensi provides an overview of his lab's projects, focusing on how mitochondrial dysfunction contributes to Alzheimer's. He highlights disturbances in brain metabolism and mitochondrial functions, the importance of sex differences, and the role of the inflammatory mediator NF Kappa B.
Join Dr. Albensi to explore innovative therapies, including computational modeling, dietary interventions, and drug treatments, aimed at improving patient care in Alzheimer's and other neurodegenerative diseases.
Key points:
00:00 Introduction
03:10 Overview of research
08:15 Importance of mitochondria in various diseases.
09:30 Alzheimer's disease and mitochondrial dysfunction.
10:30 Brain metabolism disturbances and sex differences in Alzheimer's.
14:00 Inflammatory mediator NF Kappa B.
15:30 Computational modeling of mitochondrial function.
17:00 Alzheimer's diagnosis and treatment: Challenges
19:00 Rising rates and symptoms of Alzheimer's disease.
25:15 Aging as a major risk factor for Alzheimer's.
27:30 Multifactorial nature of Alzheimer's.
29:00 Inflammation and mitochondrial dysfunction.
31:00 Trials and treatment challenges and new drugs.
35:00 Oxidative stress and antioxidants in Alzheimer's treatment.
37:00 Brain metabolism studies in Alzheimer's.
39:00 Human clinical trials on brain metabolism.
43:00 Mouse models and brain metabolism.
47:00 Sex-based differences in Alzheimer's disease.
51:00 Oxygen consumption rates and mitochondrial function.
53:00 Estradiol, creatine, and nilotinib on mitochondrial function.
59:00 Mitochondrial transplantation studies.
Dr. Benedict C. Albensi, Ph.D., BCMAS, CRQM is a distinguished neuroscientist from Greater New York, currently a full professor known for his research on Alzheimer's disease, epilepsy, traumatic brain injury, and stroke. Formerly tenured at the University of Manitoba, he leads studies on mitochondrial dysfunction, memory impairments, and inflammation in Alzheimer's through various research approaches. Continuously funded since 2005 and accordingly to Expertscape.com recognized in the top 1% globally for his number of publications over 10 years on Alzheimer's disease, Dr. Albensi excels in NF-kB signaling, clinical trials, medical imaging, and behavioral memory testing. He has presented and/or authored over 300 total seminars, abstracts, book chapters, and peer reviewed scientific papers.
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