Up to 500,000 lives could be saved under plans for the NHS in England over the next decade, health chiefs claim.
The NHS long-term plan involves greater use of high-tech treatments and diagnostic testing and could prevent 150,000 heart attacks, strokes and dementia cases.
Announcing the details in Liverpool on Monday, Theresa May said the plan was "overall" rather than specific, including improvements to social care.
"This plan is an overall plan for the NHS over the next 10 years," she said.
"It is about prevention. It's also about early diagnosis and better detection, treatment and recovery so we can ensure better outcomes.
"It's about making sure that every stage in life, the NHS is delivering that world-class care."
The prime minister announced that over the next five years the NHS budget would increase by £20.5 billion in real terms.
Mrs May said the combination of the 10-year-old plan and increased funding would "provide the certainty and long-term direction needed" to transform patient care as well as "secure the future" of the health service.
"Not everything can be done at once, so as always there will be some careful choices to make," Mrs May said.
"But delivered effectively our plan for the NHS will secure our health service for generations to come."
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