The gastrointestinal (GI) tract is a tube of connected organs that runs from the mouth to the anus. The organs of the GI tract include::
the esophagus
the stomach
the small and large intestines
Digestive enzymes in the stomach and small intestine break down nutrients in food and drink into smaller molecules that the body uses for energy, growth, and repair.
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The intestines also play an essential role in protecting the body from harmful bacteria and toxins.
Tight openings in the intestinal walls allow water and nutrients to pass through into the bloodstream while keeping harmful substances inside. In LGS, these openings become wider, allowing food particles, bacteria, and toxins to enter directly into the bloodstream.
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