This organic chemistry video tutorial on amine synthesis reactions covers a variety of topics and includes plenty of examples and practice problems to work on.
Here is a list of topics contained in this video:
1. Nomenclature of Amines - IUPAC & Common Names such as Ethanamine & Ethyl Amine
2. Aromatic Heterocycles - Pyrrole, Pyrrolidine, Pyridine, Piperidine, Pyrimidine, Imidazole, & Purine
3. Physical Properties of Amines - Boiling Point, Water Solubility, Polarity, Hydrogen Bonding
4. Basicity of Amines in Gas Phase & Aqueous Phase
5. Acidity of Amine Conjugate Acid - PKa - Electron Donating / Releasing & Withdrawing Groups
6. Quarternary Ammonium Salts - Phase Transfer Catalysts
7. Synthesis of Amines From Alkyl Halides Using NaCN, NaN3, NH3, and NaNH3 Reaction Mechanism
8. Reduction of Nitriles to Amines Using H2 With Pd, Pt, or Ni Catalyst
9. Reduction of Azides Using LiAlH4 Followed By H2O
10. Gabriel Synthesis Reactions of Primary Amines From Alkyl Halides Using H2N-NH2 or N2H4
11. Synthesis of Amino Acids From Alpha Brominated Carboxylic Acids
12. Hoffman Elimination Reaction - Amines to Alkenes Using Excess CH3I, Ag2O, H2O and Heat
13. Oxidation of Tertiary Amines to Amine Oxides Followed By Cope Elimination
14. Anti vs Syn Elimination Stereochemistry - Cope vs Hoffman - Anti-Zaitsev Regiochemistry
15. Hoffman Rearrangement of Amides to Amines Using Br2 / Cl2, OH-, and H2O
16. Curtius Rearrangement of Acid Chlorides to Amines Using NaN3, H2O, and Heat
17. Formation of Alkynes From Alkyl Halides Using NaNH2
18. Ketones to Imines & Enamines
19. Reductive Amination of Ketones Into Primary & Secondary Amines Using NaBH3CN - Sodium CyanoBorohydride
20. Conjugate Addition of Ketones & Amines
21. Formation of Oximes From Ketones Using Hydroxyl Amine - H2N-OH
22. Electrophilic Aromatic Substitution Reactions of Pyrrole at C-2 Position
23. EAS Reactions of Aromatic Heterocycles Such as Furan and Thiophene
24. Nucleophilic Aromatic Reactions of Pyridine Using NaNH2, NaOH, NaSH, CH3MgBr, and NaOCH3
25. Diazotization of Amines Using NaNO2 and HCl or HNO2 / HONO
26. Benzene to Aniline Reactions
27. Sandmeyer Reaction - CuBr, CuCl, CuCN, H3PO2, H3O+, and HBF4
28. Arenediazonium Salts and Diazocoupling
29. Formation of N-nitrosoamines from Secondary Amines
30. Synthesis Reactions - Alkane to Amine
31. Amines From Amides, Ketones, Azides, Alkyl Halides, Alcohols, Etc.
32. Side Chain Reactions of Aromatic Hetereocycles.
33. Proposed Synthesis of Piperazine From Ethane
34. Pyrrolidine to Pentane Reaction Mechanism
