醫學研究發現大蒜中的大蒜素可以抑制某些癌細胞,並且促進這些癌細胞的凋亡,例如乳癌和胃癌。有沒有人體試驗證實在人體也有這種功效呢?
參考文獻:
Bhaumika I, Pal k, Debnath U. Natural product inspired allicin analogs as novel anti-cancer agents. Bioorg Chem. 2019 May;86:259-272.
Abstract
A series of novel analogs of Allicin (S-allyl prop-2-ene-1-sulfinothioate) present in garlic has been synthesized in high yield. Synthesized 23 compounds were evaluated against different breast cancer cells (MDA-MB-468 and MCF-7) and non-cancer cells (WI38). Four compounds (3f, 3h, 3m and 3u) showed significant cytotoxicity against cancer cells whereas nontoxic to the normal cells. Based on the LD50 values and selectivity index (SI), compound 3h (S-p-methoxybenzyl (p-methoxyphenyl)methanesulfinothioate) was considered as most promising anticancer agent amongst the above three compounds. Further bio-chemical studies confirmed that compound 3h promotes ROS generation, changes in mitochondrial permeability transition and induced caspase mediated DNA damage and apoptosis.
Luo, Runlan; Fang, Dengyang; Hang, Hongdong; Tang, Zeyao .The Mechanism in Gastric Cancer Chemoprevention Source: Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry - Anti-Cancer Agents), Volume 16, Number 7, 2016, pp. 802-809(8)
Gastric cancer remains high prevalence and fatality rates in China even though its morbidity has been decreased drastically. Allicin, which is from an assistance food-garlic (Allium Sativum L), was found to be effective in gastric cancer treatment. It is a defensive substance with a board biological properties: inhibition of bacteria, fungus, virus, controlled hypertension, diabetes, and chemoprevention of several cancers, etc. Experiments have shown that allicin can be chemopreventive to gastric cancer by inhibiting the growth of cancer cells, arresting cell cycle at G2/M phase, endoplasmic reticulum (ER) stress, and mitochondria-mediated apoptosis, which includes the caspase-dependent/-independent pathways and death receptor pathway. Those mechanisms probably involve in modulating enzymatic activity, restraining DNA formation, scavenging free radicals, and affecting cell proliferation and even tumor growth. Therefore, this review is focus on the mechanism of allicin in gastric cancer.
#大蒜 #抗癌 #殺菌 #大蒜素 #大健康 #邱正宏
各位朋友,若您有醫美、減肥、健康相關問題,請用下列方法與我聯絡:
直接撥打24小時專線 +886-931919066
Line id=“Gscline"
WeChat id=“Gscline"
我有幾個不同的頻道:
Grand Health 大健康 (健康加財富、知足就是福)[ Ссылка ]
Grand Beauty 大醫美 (好好愛自己、就從現在起)[ Ссылка ]
Grand Touring 大旅遊 (大叔向前跑、永遠沒煩惱)[ Ссылка ]
歡迎大家欣賞,喜歡請按個讚,想獲取最新訊息就按「訂閱」!
我們會提供更多更新的知識和訊息給大家。
【相關連結】
每天到底要喝多少水才健康 ? 「每天要喝2.5公升的水」?已經被騙很久了,還要再騙下去嗎?
[ Ссылка ]
家用居家快篩這樣做就錯了? 方法不對也會變成偽陰性!
[ Ссылка ]
確診得到新冠肺炎後,竟然輕輕鬆鬆就痊癒了,因為做到這五件事
[ Ссылка ]
桃膠是美容聖品嗎?桃膠等於膠原蛋白嗎?吃桃膠對健康有什麼影響?
[ Ссылка ]
COVID-19疫苗副作用 ? 台灣兩大疫苗副作用解析 !
[ Ссылка ]
打完疫苗沒有症狀副作用沒有發燒,是不是疫苗沒效果?
[ Ссылка ]
一天最多吃幾顆蛋?每天要吃多少蛋? 才不會膽固醇過高
[ Ссылка ]
輕症確診,快速痊癒的秘密|與病毒共存,真相在這裡
[ Ссылка ]
我為什麼不吃,維生素D營養食品?!
[ Ссылка ]
120公斤激瘦到59公斤,短短一年內達成! 這三招科學根據說給你聽
[ Ссылка ]
不吃碳水化合物照樣讓你生病
[ Ссылка ]
經常放屁,是不是身體出問題?大腸癌跟放屁有關嗎?
[ Ссылка ]
三個原因使你越運動越胖,慘!
[ Ссылка ]
中秋烤肉?這三樣東西千萬別吃!
[ Ссылка ]
【推薦播放列表】
【健康知識】[ Ссылка ]
【減肥瘦身】[ Ссылка ]
【養身長壽】[ Ссылка ]
【Covid-19】[ Ссылка ]
【仁醫對談】[ Ссылка ]
感謝以下單位的幫助:
✪景升診所官網 [ Ссылка ]
✪邱正宏醫師網站 [ Ссылка ]
✪隆乳 [ Ссылка ]
✪自體脂肪隆乳 [ Ссылка ]
✪減肥 [ Ссылка ]
✪縮胃針(胃內肉毒) [ Ссылка ]
✪瘦臉 [ Ссылка ]
✪瘦手臂 [ Ссылка ]
✪瘦小腹 [ Ссылка ]
✪瘦小腿 [ Ссылка ]
✪瘦大腿 [ Ссылка ]
✪抽脂 [ Ссылка ]
✪男性女乳 [ Ссылка ]
✪狐臭 [ Ссылка ]
✪自體脂肪補臉 [ Ссылка ]
✪副乳修飾改善 [ Ссылка ]
✪美臀翹臀 [ Ссылка ]
✪雙下巴改善 [ Ссылка ]
✪瘦腰 [ Ссылка ]
感謝影片提供:
Thanks to [ Ссылка ] for the footages used in this video.
Thanks to [ Ссылка ] for the footages used in this video.
![](https://i.ytimg.com/vi/M03RG9gcdM8/maxresdefault.jpg)