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PRP injections are excellent treatment options for knee arthritis. It will help reduce pain and improve functional outcomes. But how and why do PRP treatments work? What is a platelet rich plasma injection? This video will review data from clinical trials which support the use of PRP therapy to treat knee osteoarthritis.

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PRP injections fall under the big umbrella category called orthobiologics or regenerative medicine. PRP is being used to treat a variety of orthopedic conditions such as injuries to muscles, tendons, ligaments, bones, and joints.

Here is a small sample of the rapidly growing body of evidence looking at using PRP injections to treat knee arthritis.

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Conclusion: Intra-articular injections of leukocyte-poor PRP can provide clinically significant functional improvement for at least 1 year in patients with mild to moderate osteoarthritis of the knee.

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Conclusion: PRP demonstrated a statistically significant improvement over CS in a 1-year follow-up.

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Conclusion: Intra-articular PRP injection appeared to be more efficacious than HA injection for the treatment of KOA in terms of short-term functional recovery. Moreover, PRP injection was superior to HA injection in terms of long-term pain relief and function improvement.

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Conclusion: These data suggest that the application of PRP in KOA patients is a treatment that could delay TKA.

Here are my takeaways after examining the evidence for using PRP to treat knee osteoarthritis. PRP is safe and effective. Symptom relief can be sustained above baseline for over one year. PRP injections may prevent the progression of osteoarthritis as indicated by potentially delaying the need for a knee replacement surgery.


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► ABOUT ME

Jeffrey Peng MD is a nonoperative orthopedist and sports medicine specialist. He created a YouTube channel and blog to translate cutting edge medical knowledge and clinical research to benefit all those looking to live an active and healthy lifestyle. He focuses on maximizing non-surgical treatments for sports injuries and orthopedic conditions. He specializes in using orthobiologics and ultrasound guided minimally invasive techniques to treat osteoarthritis, tendinopathies, and musculoskeletal disorders.

Dr. Peng is board certified in sports medicine and family medicine. He completed residency with the Stanford family medicine residency program and completed his sports medicine training with the Stanford primary care sports medicine fellowship in San Jose. He is an active faculty member for both programs and is excited about training the next generation of physicians.

Dr. Peng currently practices in Campbell, California.

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My content reflects my own opinion and does not represent the views or opinions of my employers or hospital systems I am affiliated with. They are meant for educational purposes only. They do not substitute for the medical advice of a physician. Always seek the advice of your physician with any questions you may have regarding your health.

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