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Nitrosigine is a patented ingredient from Nutrition21 that's a popular nitric oxide boosting supplement in sports nutrition. Nitrosigine has been used by some of the biggest brands in the industry, such as Animal, Ghost, GNC Beyond RAW, Dragon Pharma, RAW Nutrition, and Axe & Sledge.
Nitrosigine is a combination of arginine, silicate, and inositol, also known as inositol-stabilized arginine silicate (ASI) in the scientific literature. Typically arginine has poor bioavailability due to the first-pass effect. This means that the arginine is not properly absorbed by the body and a very small amount is available to be used to create nitric oxide. By binding arginine to silicate and adding in a small amount of inositol, Nutrition21 was able to solve the arginine dilemma.
Research has even shown that 1.5 grams of Nitrosigine are as powerful as 8 grams of citrulline malate in terms of increasing nitric oxide levels and blood flow. This is why Nitrosigine is commonly used in pre-workouts to enhance performance and muscular pumps.
However, it turns out that Nitrosigine also has some potent brain-boosting benefits as well. In this video, Ben covers a new university study that found 1.5 grams of Nitrosigine can prevent the cognitive decline that occurs with strenuous exercise.
This is really no surprise since the backbone of Nitrosigine is also used for nooLVL, another patented ingredient from Nutrition21 that's been shown to increase gaming performance. The only difference between Nitrosigine and nooLVL is that there's an extra 100 milligrams of inositol included in nooLVL for even greater cognitive benefits!
Being able to prevent that cognitive decline that occurs during exercise can be a real game-changer for competitive athletes who need maximal focus for an extended period of time.
