Two NAD+ precursors, nicotinamide riboside and nicotinamide mononucleotide, have been shown to ameliorate age-associated diseases in animals. They are well-tolerated at high doses and effectively raise NAD+ levels. Evidence suggests that these molecules, often referred to as "NAD+ boosters," may increase levels of NAD+ in humans, too; however, the doses used in some of the studies equate to far less than what was provided in the rodent studies. Currently, only nicotinamide riboside has been shown to raise plasma NAD+ levels and may possibly have beneficial health effects in humans. Future research, focused on "super boosters," may have relevance for treating complex diseases such as diabetes, heart disease, cancer, and Alzheimer's. In this clip, Dr. David Sinclair discusses the current state of research on the NAD+ boosters nicotinamide riboside and nicotinamide mononucleotide.

This clip was taken from the FoundMyFitness interview with Dr. David Sinclair found at [ Ссылка ]

Original episode published on Nov 6, 2019
⏳ #Aging #Resveratrol #Epigenetics 🧬

About FoundMyFitness: Rhonda Patrick has a Ph.D. in biomedical science from the University of Tennessee Health Science Center, and St. Jude Children’s Research Hospital. She also has a Bachelor’s of Science degree in biochemistry/chemistry from the University of California. She has done extensive research on aging, cancer, and nutrition.

It is Dr. Patrick’s goal to challenge the status quo and encourage the wider public to think about health and longevity using a proactive, preventative approach.

Learn more about Dr. Rhonda Patrick and her mission for FoundMyFitness at www.foundmyfitness.com

About David Sinclair: David A. Sinclair, PhD, is a professor in the Department of Genetics at Harvard Medical School and co-director of the Paul F. Glenn Center for the Biological Mechanisms of Aging. He is the co-founder of the journal Aging, where he serves as co-chief editor. His work on aging has earned him numerous awards for his research, including the Australian Medical Research Medal, and landed him a spot in Time magazine's Top 100 most influential people on the planet. Learn more about David Sinclair at [ Ссылка ]

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