At the onset of the COVID-19 pandemic, efforts to develop drugs and vaccines were hampered by the limited knowledge of the molecular details of how SARS-CoV-2 infects cells.

In this webinar, UCSF professors Brian Shoichet and Nevan Krogan discussed their work in mapping out virus-human protein interactions, and the subsequent identification of known drugs that exhibit antiviral activities by targeting human proteins. They also shared strategies used to coordinate this large-scale project which was published in a Nature article with more than 100 co-authors.

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