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పెయిన్ కిల్లర్స్ ఎలా పని చేస్తాయి ? By Dr.GPV Subbaiah Spine Surgeon Care Hospital Hyderabad From Dr.GPV Subbaiah Health Info
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పెయిన్ కిల్లర్స్ టాబ్లెట్స్
పెయిన్ కిల్లర్స్ వాడటం వలన వచ్చే సమస్య
ఏ పెయిన్ కిల్లర్స్ సురక్షితం
Mechanism of action of pain killers
side effects of taking pain killers in telugu
How do painkillers work?
What are the different types of painkillers?
How do NSAIDs reduce pain and inflammation?
What are the side effects of opioids?
How does acetaminophen relieve pain and reduce fever?
Are there any natural alternatives to painkillers?
What are the risks of long-term painkiller use?
Can painkillers be addictive?
How do local anesthetics work?
Are there any precautions or interactions with painkiller medications?
Painkiller medicines, also known as analgesics, work by targeting the pain receptors in the body and reducing the perception of pain. There are different types of painkillers, and they work through various mechanisms. Here are some common ways in which painkiller medicines work:
Nonsteroidal Anti-Inflammatory Drugs (NSAIDs):
NSAIDs, such as ibuprofen, aspirin, and naproxen, work by inhibiting an enzyme called cyclooxygenase (COX). COX is responsible for the production of prostaglandins, which are chemicals that contribute to pain, inflammation, and fever. By blocking the action of COX, NSAIDs reduce the production of prostaglandins, which leads to pain relief and reduced inflammation.
Opioids:
Opioids, such as morphine, codeine, and oxycodone, work by binding to opioid receptors in the brain, spinal cord, and other parts of the body. These receptors are involved in the modulation of pain signals. When opioids bind to these receptors, they inhibit the transmission of pain signals and produce analgesia. Opioids can provide powerful pain relief, particularly for severe pain, but they also carry risks of side effects and potential dependence or addiction.
Acetaminophen:
Acetaminophen (paracetamol) is another common painkiller that works by affecting the central nervous system. Its exact mechanism of action is not fully understood, but it is believed to reduce pain and fever by inhibiting certain enzymes in the brain. Unlike NSAIDs, acetaminophen has minimal anti-inflammatory effects and primarily acts as an analgesic and fever reducer.
Local Anesthetics:
Local anesthetics, such as lidocaine, work by temporarily blocking nerve signals in a specific area of the body. They achieve this by blocking sodium channels, which are responsible for transmitting pain signals. By preventing the nerve signals from reaching the brain, local anesthetics provide temporary pain relief in the localized area where they are applied or injected.
Adjuvant Analgesics:
Adjuvant analgesics are medications that were originally developed for other purposes but have shown effectiveness in relieving certain types of pain. Examples include antidepressants, anticonvulsants, and muscle relaxants. These medications may work by affecting neurotransmitters or altering the way pain signals are processed by the central nervous system.
It's important to note that painkiller medicines provide temporary relief from pain symptoms but do not address the underlying cause of pain. The choice of painkiller medication depends on the type and severity of pain, individual factors, and the guidance of a healthcare professional. It is crucial to follow proper dosing instructions and consult a healthcare provider for appropriate use and potential side effects or interactions with other medications.
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