This animation is about a Real Leptospirosis case I encountered during my training at Medical ICU. I talk about Microbiology, The initial symptoms, Complications & treatments for the disease. The causative bacteria are Leptospira, a zoonotic species that spread via the urine of infected rats, dogs & cattle. During the Immunological phase, the body produces antibodies against the pathogen. But these antibodies also attack the Liver, Kidneys & Other organs including blood vessels. The gold standard test is the Microscopic Agglutination test. The diagnosis is mainly clinical, & needs prompt treatment with Antibiotics (Cephalosporins, Penicillin). We arranged urgent Plasma exchange (plasmapheresis) for this patient as he developed severer pulmonary hemorrhages.
The Table of content.
00:00 Introduction
00:13 Microbiology (Leptospira)
01:03 Pathophysiology of Leptospirosis
01:32 Symptoms and Signs of Leptospirosis
02:03 Pulmonary Hemorrhage
02:22 Renal & Hepatic Failure
02:52 Investigations
03:22 Treatment of Leptospirosis
03:37 Plasma Exchange Therapy
Special Thanks: to Daci Sky for suggesting This Topic.
References:
1) Kumar and Clark's Clinical Medicine (10th Edition).
2) UpToDate page on Leptospirosis: [ Ссылка ]
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