Great results need a great method. In order to compare different lots of material or different manufacturing approaches, variation due to sample preparation should be minimized. Should the sample be run in suspension or as a dry powder? What salts or surfactants are needed for the suspension? How much energy should be applied and how? Systematically determining the answers to these questions is method development.
Dr. Jeff Bodycomb leads an in-depth discussion of what to do before your sample reaches the analyzer.
