This video discusses the personal fat threshold hypothesis, a key concept in the development of insulin resistance and type 2 diabetes.
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- VIDEO DESCRIPTION -
Being overweight or obese is associated with a substantially increased risk of becoming insulin-resistant and developing type 2 diabetes.
However, not everyone with obesity is insulin resistant, and many people with even morbid obesity never develop diabetes. At the same time, some people develop type 2 diabetes even though they are barely overweight or even have a body mass index in the normal range, while others are obese and never develop diabetes. How can these observations be reconciled?
The cumulative evidence on the topic suggests a model called the personal fat threshold hypothesis. This hypothesis posits that insulin resistance and glucose intolerance are associated with fat accumulation in some tissues, whereas fat accumulation in others is metabolically benign.
In this video, we will thoroughly review the personal fat threshold hypothesis, how fat tissue works, and what happens inside the body when fat can no longer be safely stored.
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0:00 Introduction
04:18 Weight Gain is Associated With an Increase in Insulin Resistance
08:37 How Fat Can Safely Be Stored in the Body
10:53 The Type of Body Fat that Triggers Insulin Resistance
13:15 How Fat Tissue Works
23:49 The Personal Fat Threshold
26:37 What is the Evidence Supporting the Personal Fat Threshold Hypothesis?
30:00 Why is the Personal Fat Threshold Hypothesis Relevant?
32:30 How Do We Know Whether We Have Crossed Our Own Personal Fat Threshold?
35:43 Summary
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Causes of Insulin Resistance: The Personal Fat Threshold
Теги
insulin resistancetype 2 diabetesinsulin resistance dietinsulin sensitivityglucose toleranceglucose intolerancediabetes mellitustype 2 diabetes mellitusinsulinglucosesugarblood sugarblood glucoseblood insulinhyperinsulinemiacarbscarbohydratesectopic fatvisceral fatsubcutaneous fatpersonal fat thresholddr. roy taylorroy taylordietnutritiondiabetes and nutritionprevention of diabetesdiabetes diet