Two NAD+ precursors, nicotinamide riboside and nicotinamide mononucleotide, have been shown to ameliorate age-associated diseases in animals. They are well-tolerated at high doses and effectively raise NAD+ levels. These molecules are not shelf-stable at high temperatures or in conditions of high humidity, however. They quickly degrade into nicotinamide, which inhibits the activity of sirtuins and PARP, a DNA repair enzyme. In this clip, Dr. David Sinclair discusses the stability issues encountered in some storage conditions.
This clip was taken from the FoundMyFitness interview with Dr. David Sinclair found at [ Ссылка ]
Original episode published on Nov 6, 2019
⏳ #Aging #Resveratrol #Epigenetics 🧬
About FoundMyFitness: Rhonda Patrick has a Ph.D. in biomedical science from the University of Tennessee Health Science Center, and St. Jude Children’s Research Hospital. She also has a Bachelor’s of Science degree in biochemistry/chemistry from the University of California. She has done extensive research on aging, cancer, and nutrition.
It is Dr. Patrick’s goal to challenge the status quo and encourage the wider public to think about health and longevity using a proactive, preventative approach.
Learn more about Dr. Rhonda Patrick and her mission for FoundMyFitness at www.foundmyfitness.com
