Key Concepts
1. Membrane attack complex (MAC) or C5b-C9 from on cells membrane and lyses pathogens
2. All pathways (the classical, lectin and alternative pathways) are similar from C5 cleavage until formation of MAC.
3. C5 convertases of Alternative pathway (C3bBbC3b) and Lectin and classical pathways (C4bC2bC3b) cleave C5 to start the formation of MAC
