DHEA is an adrenal hormone that starts to decline in your 20s; it's linked with a host of health benefits.
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-----------------------------------------Show Notes--------------------------------------
0:00 Intro
0:03 DHEA is hormone. It begins to decline at about age 25.
0:07 At age 60 or 70, DHEA production has declined by about 90%.
0:13 DHEA is linked with immune health, metabolic health, memory, and cognition.
0:21 After menopause, adrenals become the sole source of androgens in the body.
0:45 Consider taking DHEA before trying hormone replacement therapy.
2:00 Active DHEA is made by your adrenals. It is in equilibrium with DHEA-S (DHEA-sulfate).
2:30 Metabolites adhere to a circadian rhythm. Be consistent about bloodwork timing.
3:45 DHEA gets converted to 4-dione, then, through aromatization, into estrogen.
6:55 Low DHEA sulfate levels are linked with higher mortality and disease.
7:25 DHEA supplementation in incorrect doses can accelerate hair loss and increase estrogen.
8:00 Dosing Men: 10 mg/ 10 years of life. Pay attention to your body’s feedback.
9:00 Dosing Women: 75% less than men. 10 mg/ 10 years of life multiplied by .25 (25%)
12:45 Micronized DHEA may be a little better absorbed. Transdermal is not necessary.
14:10 Women with PCOS should not take DHEA.
15:00 Insulin drives androgens in women. Spironolactone, a med taken for PCOS, is an antiandrogen.
15:50 Work with your doctor. Test your DHEA sulfate blood levels.
16:55 Low doses of estrogen has benefits for men in their cognition, brain function and mental health.
